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首页> European journal of pharmacology> Trimethylamine N-oxide promotes abdominal aortic aneurysm by inducing vascular inflammation and vascular smooth muscle cell phenotypic switching.

Trimethylamine N-oxide promotes abdominal aortic aneurysm by inducing vascular inflammation and vascular smooth muscle cell phenotypic switching.

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作者： Bo,Wei ^[1] ; Na,Deng ^[1] ; Haijun,Guo ^[1] ; Yingying,Wei ^[1] ; Fujia,Xu ^[1] ; Sihan,Luo ^[1] ; Weili,You ^[1] ; Jingjing,Chen ^[1] ; Wei,Li ^[2] ; Xiaoyun,Si ^[3]

作者单位： Department of Cardiology, Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Road, Guiyang, 550004, Guizhou Province, China. ^[1] Department of Cardiology, Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Road, Guiyang, 550004, Guizhou Province, China. Electronic address: liwei01@gmc.edu.cn. ^[2] Department of Cardiology, Affiliated Hospital of Guizhou Medical University, No. 28 Guiyi Road, Guiyang, 550004, Guizhou Province, China. Electronic address: sixiaoyun@gmc.edu.cn. ^[3]

关键词 Aortic aneurysm Inflammation Macrophage Nuclear factor-κB signaling Trimethylamine N-Oxide Vascular smooth muscle cell

主题词人类(Humans);动物(Animals);NF-κB(NF-kappa B);肌, 平滑, 血管(Muscle, Smooth, Vascular);主动脉瘤, 腹(Aortic Aneurysm, Abdominal);炎症(Inflammation);肌细胞, 平滑肌(Myocytes, Smooth Muscle);血管紧张素Ⅱ(Angiotensin II);疾病模型, 动物(Disease Models, Animal);甲胺类(Methylamines)

DOI 10.1016/j.ejphar.2023.176307

PMID 38160930

发布时间 2024-02-05

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European journal of pharmacology

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