Association between single nucleotide polymorphisms, TGF-β1 promoter methylation, and polycystic ovary syndrome.

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作者： Mengge,Gao ^[1] ; Xiaohua,Liu ^[2] ; Heng,Gu ^[3] ; Hang,Xu ^[1] ; Wenyao,Zhong ^[1] ; Xiangcai,Wei ^[1] ; Xingming,Zhong ^[2]

作者单位： NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Guangzhou, China. ^[1] Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, Guangdong, 510630, China. ^[2] Department of Clinical Nutrition, Huadu District People's Hospital, 48 Xinhua Road, Huadu, Guangzhou, Guangdong, 510800, China. ^[3] Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, Guangdong, 510630, China. dxcwei@163.com. ^[4] Guangdong Women and Children Hospital, Guangzhou, China. dxcwei@163.com. ^[5] NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Guangzhou, China. xingmingzh@126.com. ^[6] Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, Guangdong, 510630, China. xingmingzh@126.com. ^[7]

关键词 DNA methylation Insulin resistance PCOS epigenetics Polycystic ovary syndrome Single nucleotide polymorphism TGF-β1 Transforming growth factor β1 Whole exome sequencing