Development of Small-Molecule Anti-HIV-1 Agents Targeting HIV-1 Capsid Proteins.

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作者： Takuya,Kobayakawa ^[1] ; Masaru,Yokoyama ^[2] ; Kohei,Tsuji ^[1] ; Sayaka,Boku ^[1] ; Masaki,Kurakami ^[1] ; Masayuki,Fujino ^[3] ; Takahiro,Ishii ^[1] ; Yutaro,Miura ^[1] ; Soshi,Nishimura ^[1] ; Kouki,Shinohara ^[1] ; Kenichi,Yamamoto ^[1] ; Peter,Bolah ^[1] ; Osamu,Kotani ^[2] ; Tsutomu,Murakami ^[3] ; Hironori,Sato ^[2] ; Hirokazu,Tamamura ^[1]

作者单位： Department of Medicinal Chemistry, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU). ^[1] Pathogen Genomics Center, National Institute of Infectious Diseases. ^[2] AIDS Research Center, National Institute of Infectious Diseases. ^[3]

关键词 anti-human immunodeficiency virus (HIV)capsid dipeptide mimic in silico screening

主题词人类(Humans);抗HIV药(Anti-HIV Agents);病毒壳体(Capsid);衣壳蛋白质类(Capsid Proteins);HIV-1(HIV-1);病毒装配(Virus Assembly)

DOI 10.1248/cpb.c23-00618

PMID 38171903

发布时间 2025-01-14

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