Desulfovibrio vulgaris interacts with novel gut epithelial immune receptor LRRC19 and exacerbates colitis.

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作者： Runxiang,Xie ^[1] ; Yu,Gu ^[1] ; Mengfan,Li ^[1] ; Lingfeng,Li ^[1] ; Yunwei,Yang ^[1] ; Yue,Sun ^[1] ; Bingqian,Zhou ^[1] ; Tianyu,Liu ^[1] ; Sinan,Wang ^[1] ; Wentian,Liu ^[1] ; Rongcun,Yang ^[2] ; Xiaomin,Su ^[3] ; Weilong,Zhong ^[4] ; Bangmao,Wang ^[5] ; Hailong,Cao ^[6]

作者单位： Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. ^[1] Department of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China. ^[2] Department of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China. xiaominsu@nankai.edu.cn. ^[3] Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. zhongweilong@tmu.edu.cn. ^[4] Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. caohailong@tmu.edu.cn. ^[5] Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, China. mwang02@tmu.edu.cn. ^[6]

关键词 Flagellin Leucine-rich repeat C19 Typhaneoside Ulcerative colitis

主题词人类(Humans);小鼠(Mice);动物(Animals);Toll样受体5(Toll-Like Receptor 5);普通脱硫弧菌(Desulfovibrio vulgaris);结肠炎(Colitis);结肠炎, 溃疡性(Colitis, Ulcerative);炎症(Inflammation);硫酸葡聚糖(Dextran Sulfate);疾病模型, 动物(Disease Models, Animal);小鼠, 近交C57BL(Mice, Inbred C57BL);结肠(Colon);受体, 细胞表面(Receptors, Cell Surface)

DOI 10.1186/s40168-023-01722-8

PMID 38172943

发布时间 2024-01-06

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Microbiome

2024年12卷1期

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Desulfovibrio vulgaris interacts with novel gut epithelial immune receptor LRRC19 and exacerbates colitis.

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Desulfovibrio vulgaris interacts with novel gut epithelial immune receptor LRRC19 and exacerbates colitis.

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