首页> European journal of pharmacology> Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p/IGF1 receptor/ERK.

Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p/IGF1 receptor/ERK.

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第一作者： Ming-Hui,Li

第一单位： College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China; Department of Pharmacy, Ningbo Municipal Hospital of Traditional Chinese Medicine, Ningbo, China; Henan International Joint Laboratory of Cardiovascular Remodeling and Drug Intervention, Xinxiang, 453003, China; Xinxiang Key Laboratory of Vascular Remodeling Intervention and Molecular Targeted Therapy Drug Development, Xinxiang, 453003, China.

作者： Ming-Hui,Li ^[1] ; Xu,Liu ^[2] ; Yu-Liang,Xie ^[3] ; Xiao-Guang,Tang ^[3] ; Liao-Fan,Song ^[3] ; Fan-Rong,Zhao ^[3] ; Yu-Jing,Chen ^[3] ; Chao,Guo ^[3] ; Wei-Fang,Zhang ^[4] ; Tian-Tian,Zhu ^[5]

作者单位： College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China; Department of Pharmacy, Ningbo Municipal Hospital of Traditional Chinese Medicine, Ningbo, China; Henan International Joint Laboratory of Cardiovascular Remodeling and Drug Intervention, Xinxiang, 453003, China; Xinxiang Key Laboratory of Vascular Remodeling Intervention and Molecular Targeted Therapy Drug Development, Xinxiang, 453003, China. ^[1] Department of Pharmacy, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China. ^[2] College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China; Henan International Joint Laboratory of Cardiovascular Remodeling and Drug Intervention, Xinxiang, 453003, China; Xinxiang Key Laboratory of Vascular Remodeling Intervention and Molecular Targeted Therapy Drug Development, Xinxiang, 453003, China. ^[3] Departments of Pharmacy, The Second Affiliated Hospital, Nanchang University, Nanchang, China. Electronic address: z_weifang@163.com. ^[4] College of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, China; Department of Pharmacy, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China; Henan International Joint Laboratory of Cardiovascular Remodeling and Drug Intervention, Xinxiang, 453003, China; Xinxiang Key Laboratory of Vascular Remodeling Intervention and Molecular Targeted Therapy Drug Development, Xinxiang, 453003, China. Electronic address: zhutt@xxmu.edu.cn. ^[5]

关键词 IGF1 receptor Let-7g-5p LncRNA H19 PAH Right ventricular hypertrophy Sodium butyrate