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Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy.

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第一作者: Zhangyi,Luo
第一单位: Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.;UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
作者: Zhangyi,Luo [1] ; Yixian,Huang [1] ; Neelu,Batra [2] ; Yuang,Chen [1] ; Haozhe,Huang [1] ; Yifei,Wang [1] ; Ziqian,Zhang [1] ; Shichen,Li [1] ; Chien-Yu,Chen [1] ; Zehua,Wang [1] ; Jingjing,Sun [1] ; Qiming Jane,Wang [3] ; Da,Yang [1] ; Binfeng,Lu [4] ; James F,Conway [5] ; Lu-Yuan,Li [6] ; Ai-Ming,Yu [2] ; Song,Li [7]
作者单位: Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA.;UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. [1] Department of Biochemistry and Molecular Medicine, University of California, Davis, School of Medicine, Sacramento, CA, USA. [2] Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. [3] Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA. [4] Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. [5] UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.;State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin, China. [6] Center for Pharmacogenetics, Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA. sol4@pitt.edu.;UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA. sol4@pitt.edu. [7]
DOI 10.1038/s41467-023-44572-6
PMID 38177179
发布时间 2026-03-07
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