Methotrimeprazine is a neuroprotective antiviral in JEV infection via adaptive ER stress and autophagy.

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作者： Surendra K,Prajapat ^[1] ; Laxmi,Mishra ^[1] ; Sakshi,Khera ^[1] ; Shadrack D,Owusu ^[1] ; Kriti,Ahuja ^[2] ; Puja,Sharma ^[3] ; Eira,Choudhary ^[1] ; Simran,Chhabra ^[1] ; Niraj,Kumar ^[1] ; Rajan,Singh ^[4] ; Prem S,Kaushal ^[5] ; Dinesh,Mahajan ^[6] ; Arup,Banerjee ^[4] ; Rajender K,Motiani ^[7] ; Sudhanshu,Vrati ^[1] ; Manjula,Kalia ^[3]

作者单位： Virology Research Group, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, 121001, India. ^[1] Institut de Biologie Moléculaire et Cellulaire (IBMC), Université de Strasbourg, 67000, Strasbourg, France. ^[2] Laboratory of Calciomics and Systemic Pathophysiology, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, 121001, India. ^[3] Structural Biology & Translation Regulation Laboratory, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, 121001, India. ^[4] Advanced Technology Platform Centre, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, 121001, India. ^[5] Department of Life Sciences, Shiv Nadar University, Greater Noida, 201314, India. ^[6] Chemistry and Pharmacology Lab, Centre for Drug Design and Discovery, Translational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad, 121001, India. ^[7] Virology Research Group, Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, 121001, India. manjula@rcb.res.in. ^[8]

关键词 Antipsychotic Microglia Neuroinflammation Phenothiazines Trifluoperazine