Tumour-based Mutational Profiles Predict Visceral Metastasis Outcome and Early Death in Prostate Cancer Patients.

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作者： Olivier,Cussenot ^[1] ; Kirsten M,Timms ^[2] ; Emmanuel,Perrot ^[3] ; Pascal,Blanchet ^[3] ; Laurent,Brureau ^[3] ; Cara,Solimeno ^[2] ; Gaelle,Fromont ^[4] ; Eva,Comperat ^[5] ; Geraldine,Cancel-Tassin ^[6]

作者单位： CeRePP, Paris, France; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK. ^[1] Myriad Genetics, Salt Lake City, UT, USA. ^[2] Department of Urology, CHU Pointe-a-Pitre/Abymes, Pointe-à-Pitre, Guadeloupe, France; Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, Guadeloupe, France. ^[3] CeRePP, Paris, France; Faculté de Médecine, Inserm UMR1069 "Nutrition, Croissance et Cancer" Université François Rabelais, Tours, France; Departments of Pathology and Urology, CHRU Bretonneau, Tours, France. ^[4] CeRePP, Paris, France; Department of Pathology, Medical University of Vienna, Vienna, Austria. ^[5] CeRePP, Paris, France; GRC n°5 Predictive Onco-Urology, Sorbonne Université, Paris, France. Electronic address: g.cancel@cerepp.org. ^[6]

关键词 DNA repair Genes Germline Metastasis Mutation Prostate cancer Somatic

主题词人类(Humans);男(雄)性(Male);老年人(Aged);前列腺肿瘤(Prostatic Neoplasms);突变(Mutation);中年人(Middle Aged);老年人, 80以上(Aged, 80 and over);腺瘤状结肠息肉蛋白质(Adenomatous Polyposis Coli Protein);β连环素(beta Catenin);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);预后(Prognosis);BRCA2蛋白质(BRCA2 Protein);Kaplan-Meiers评估(Kaplan-Meier Estimate);骨肿瘤(Bone Neoplasms);肿瘤转移(Neoplasm Metastasis);比例危险度模型(Proportional Hazards Models);淋巴转移(Lymphatic Metastasis);微卫星不稳定性(Microsatellite Instability)

DOI 10.1016/j.euo.2023.12.003

PMID 38182487

发布时间 2024-05-17

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European urology oncology

2024年7卷3期

597-604页

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Tumour-based Mutational Profiles Predict Visceral Metastasis Outcome and Early Death in Prostate Cancer Patients.

European urology oncology

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European urology oncology

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Tumour-based Mutational Profiles Predict Visceral Metastasis Outcome and Early Death in Prostate Cancer Patients.

European urology oncology

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European urology oncology

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