作者:
Matthew,Tegtmeyer [1]
;
Jatin,Arora [2]
;
Samira,Asgari [3]
;
Beth A,Cimini [4]
;
Ajay,Nadig [5]
;
Emily,Peirent [6]
;
Dhara,Liyanage [7]
;
Gregory P,Way [4]
;
Erin,Weisbart [5]
;
Aparna,Nathan [6]
;
Tiffany,Amariuta [7]
;
Kevin,Eggan [8]
;
Marzieh,Haghighi [9]
;
Steven A,McCarroll [10]
;
Luke,O'Connor [1]
;
Anne E,Carpenter [7]
;
Shantanu,Singh [11]
;
Ralda,Nehme [1]
;
Soumya,Raychaudhuri [1]
作者单位:
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[1]
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
[2]
Centre for Gene Therapy and Regenerative Medicine, King's College, London, UK.
[3]
Center for Data Sciences, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
[4]
Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
[5]
Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
[6]
Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[7]
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
[8]
Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
[9]
Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[10]
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
[11]
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
[12]
Halıcıoğlu Data Science Institute, University of California, La Jolla, CA, USA.
[13]
Department of Medicine, University of California, La Jolla, CA, USA.
[14]
Department of Genetics, Harvard Medical School, Boston, MA, USA.
[15]
Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA. shsingh@broadinstitute.org.
[16]
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. rnehme@broadinstitute.org.
[17]
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. rnehme@broadinstitute.org.
[18]
Center for Data Sciences, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. soumya@broadinstitute.org.
[19]
Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. soumya@broadinstitute.org.
[20]
Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. soumya@broadinstitute.org.
[21]
Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. soumya@broadinstitute.org.
[22]
Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. soumya@broadinstitute.org.
[23]
Centre for Genetics and Genomics Versus Arthritis, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK. soumya@broadinstitute.org.
[24]
主题词
染色体图(Chromosome Mapping);数量性状基因座位(Quantitative Trait Loci);细胞核(Cell Nucleus);细胞形状(Cell Shape);诱导多能干细胞(Induced Pluripotent Stem Cells);突变蛋白质类(Mutant Proteins)
DOI
10.1038/s41467-023-44045-w
PMID
38184653
发布时间
2024-06-22
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Nature communications
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