Decaging-to-labeling: Development and investigation of quinone methide warhead for protein labeling.

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第一作者： Fuhu,Guo

第一单位： Synthetic and Functional Biomolecules Center, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

作者： Fuhu,Guo ^[1] ; Shengnan,Qin ^[1] ; Ziqi,Liu ^[2] ; Peng R,Chen ^[3] ; Xinyuan,Fan ^[4]

作者单位： Synthetic and Functional Biomolecules Center, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. ^[1] Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China. ^[2] Synthetic and Functional Biomolecules Center, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China. Electronic address: pengchen@pku.edu.cn. ^[3] Synthetic and Functional Biomolecules Center, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China. Electronic address: xinyuanfan@pku.edu.cn. ^[4]

关键词 Bioorthogonal photocatalysis Decaging-to-labeling Protein labeling Proximity labeling Quinone methide

主题词氨基酸序列(Amino Acid Sequence);蛋白质组学(Proteomics);蛋白质类(Proteins);吲哚醌类(Indolequinones)

DOI 10.1016/j.bioorg.2023.107088

PMID 38194902

发布时间 2024-01-24

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