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Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia.

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第一作者： Samuli,Eldfors

第一单位： Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Department of Internal Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland.;Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA.;Department of Medicine, Harvard Medical School, Boston, MA.

作者： Samuli,Eldfors ^[1] ; Joseph,Saad ^[2] ; Nemo,Ikonen ^[3] ; Disha,Malani ^[4] ; Markus,Vähä-Koskela ^[3] ; Bjørn T,Gjertsen ^[5] ; Mika,Kontro ^[6] ; Kimmo,Porkka ^[7] ; Caroline A,Heckman ^[3]

作者单位： Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Department of Internal Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland.;Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA.;Department of Medicine, Harvard Medical School, Boston, MA. ^[1] Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.;iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland. ^[2] Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland. ^[3] Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Department of Medicine, Harvard Medical School, Boston, MA.;Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA. ^[4] Department of Medicine, Hematology Section, Haukeland University Hospital, Bergen, Norway.;Department of Clinical Science, Center for Cancer Biomarkers, University of Bergen, Bergen, Norway. ^[5] Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.;Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.;Foundation for the Finnish Cancer Institute, Helsinki, Finland. ^[6] Department of Internal Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland.;iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland.;Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland. ^[7]

医学主题词人类(Humans);烟酰胺磷酸核糖基转移酶(Nicotinamide Phosphoribosyltransferase);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);染色体缺失(Chromosome Deletion);抗肿瘤药(Antineoplastic Agents);染色体, 人, 7对(Chromosomes, Human, Pair 7)

DOI 10.1182/bloodadvances.2023010435

PMID 38197948

发布时间 2024-11-05

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Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia.

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Monosomy 7/del(7q) cause sensitivity to inhibitors of nicotinamide phosphoribosyltransferase in acute myeloid leukemia.

Blood advances

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