Impact of OPRM1 (Mu-opioid Receptor Gene) A112G Polymorphism on Dual Oxycodone and Cocaine Self-administration Behavior in a Mouse Model.

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第一作者： Yong,Zhang

第一单位： Laboratory of the Biology of Addictive Diseases, the Rockefeller University, New York, NY 10065, United States. Electronic address: yong.zhang14@login.cuny.edu.

作者： Yong,Zhang ^[1] ; Matthew,Randesi ^[2] ; Julie A,Blendy ^[3] ; Mary Jeanne,Kreek ^[2] ; Eduardo R,Butelman ^[4]

作者单位： Laboratory of the Biology of Addictive Diseases, the Rockefeller University, New York, NY 10065, United States. Electronic address: yong.zhang14@login.cuny.edu. ^[1] Laboratory of the Biology of Addictive Diseases, the Rockefeller University, New York, NY 10065, United States. ^[2] Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. ^[3] Laboratory of the Biology of Addictive Diseases, the Rockefeller University, New York, NY 10065, United States; Neuropsychoimaging of Addictions and Related Conditions Research Program, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States. ^[4]

关键词 A112G mice Pdyn, Fkbp5, Oprk1 and Oprm1 mRNA expression cocaine oxycodone polydrug use sequential use of oxycodone and cocaine