Simplified drug efficacy evaluation system for vasopressin neurodegenerative disease using mouse disease-specific induced pluripotent stem cells.

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第一作者： Tsutomu,Miwata

第一单位： Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan.

作者： Tsutomu,Miwata ^[1] ; Hidetaka,Suga ^[2] ; Kazuki,Mitsumoto ^[3] ; Jun,Zhang ^[4] ; Yoshimasa,Hamada ^[4] ; Mayu,Sakakibara ^[1] ; Mika,Soen ^[1] ; Hajime,Ozaki ^[1] ; Tomoyoshi,Asano ^[1] ; Takashi,Miyata ^[1] ; Yohei,Kawaguchi ^[1] ; Yoshinori,Yasuda ^[1] ; Tomoko,Kobayashi ^[1] ; Mariko,Sugiyama ^[1] ; Takeshi,Onoue ^[1] ; Daisuke,Hagiwara ^[1] ; Shintaro,Iwama ^[1] ; Seiichi,Oyadomari ^[4] ; Hiroshi,Arima ^[1]

作者单位： Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan. ^[1] Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: sugahide@med.nagoya-u.ac.jp. ^[2] Department of Endocrinology and Diabetes, Gifu Prefectural Tajimi Hospital, Tajimi, Japan. ^[3] Division of Molecular Biology, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan. ^[4]

关键词 Familial neurohypophyseal diabetes insipidus Mouse disease-specific induced pluripotent stem cells Mutant neurophysin II Neurodegenerative disease Semi-quantification Vasopressin neurons