首页> Virchows Archiv : an international journal of pathology> Intratumoral heterogeneity of Ki67 proliferation index outperforms conventional immunohistochemistry prognostic factors in estrogen receptor-positive HER2-negative breast cancer.

Intratumoral heterogeneity of Ki67 proliferation index outperforms conventional immunohistochemistry prognostic factors in estrogen receptor-positive HER2-negative breast cancer.

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第一作者： Dovile,Zilenaite-Petrulaitiene

第一单位： Institute of Informatics, Faculty of Mathematics and Informatics, Vilnius University, Naugarduko Str. 24, 03225, Vilnius, Lithuania. dovile.zilenaite@vpc.lt.;Department of Pathology and Forensic Medicine, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, M. K. Ciurlionio Str. 21, 03101, Vilnius, Lithuania. dovile.zilenaite@vpc.lt.;National Centre of Pathology, affiliate of Vilnius University Hospital Santaros Klinikos, P. Baublio Str. 5, 08406, Vilnius, Lithuania. dovile.zilenaite@vpc.lt.

作者： Dovile,Zilenaite-Petrulaitiene ^[1] ; Allan,Rasmusson ^[2] ; Justinas,Besusparis ^[2] ; Ruta Barbora,Valkiuniene ^[2] ; Renaldas,Augulis ^[2] ; Aida,Laurinaviciene ^[2] ; Benoit,Plancoulaine ^[3] ; Linas,Petkevicius ^[4] ; Arvydas,Laurinavicius ^[2]

作者单位： Institute of Informatics, Faculty of Mathematics and Informatics, Vilnius University, Naugarduko Str. 24, 03225, Vilnius, Lithuania. dovile.zilenaite@vpc.lt.;Department of Pathology and Forensic Medicine, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, M. K. Ciurlionio Str. 21, 03101, Vilnius, Lithuania. dovile.zilenaite@vpc.lt.;National Centre of Pathology, affiliate of Vilnius University Hospital Santaros Klinikos, P. Baublio Str. 5, 08406, Vilnius, Lithuania. dovile.zilenaite@vpc.lt. ^[1] Department of Pathology and Forensic Medicine, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, M. K. Ciurlionio Str. 21, 03101, Vilnius, Lithuania.;National Centre of Pathology, affiliate of Vilnius University Hospital Santaros Klinikos, P. Baublio Str. 5, 08406, Vilnius, Lithuania. ^[2] Department of Pathology and Forensic Medicine, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, M. K. Ciurlionio Str. 21, 03101, Vilnius, Lithuania.;Path-Image/BioTiCla, University of Caen Normandy, François Baclesse Comprehensive Cancer Center, 3 Av. du Général Harris, 14000, Caen, France. ^[3] Institute of Informatics, Faculty of Mathematics and Informatics, Vilnius University, Naugarduko Str. 24, 03225, Vilnius, Lithuania. ^[4]

关键词 Breast cancer Digital image analysis Haralick’s texture entropy Immunohistochemistry Intratumoral heterogeneity Ki67 proliferation rate