首页> Acta pharmacologica Sinica> CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice.

CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice.

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第一作者： Fu-Wen,Zuo

第一单位： Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China.

作者： Fu-Wen,Zuo ^[1] ; Zhi-Yong,Liu ^[1] ; Ming-Wei,Wang ^[1] ; Jun-Yao,Du ^[1] ; Peng-Zhong,Ding ^[1] ; Hao-Ran,Zhang ^[1] ; Wei,Tang ^[2] ; Yu,Sun ^[1] ; Xiao-Jie,Wang ^[1] ; Yan,Zhang ^[1] ; Yu-Sheng,Xie ^[1] ; Ji-Chao,Wu ^[1] ; Min,Liu ^[3] ; Zi-Ying,Wang ^[4] ; Fan,Yi ^[5]

作者单位： Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China. ^[1] Department of Pathogenic Biology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China. ^[2] Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China. liuweimin@sdu.edu.cn. ^[3] Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China. wangziying@sdu.edu.cn. ^[4] Department of Pharmacology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, China. fanyi@sdu.edu.cn.;National Key Laboratory for Innovation and Transformation of Luobing Theory, Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, 250012, China. fanyi@sdu.edu.cn. ^[5]

关键词 CCDC92 cholesterol efflux diabetic kidney disease podocytes proteasome activity