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D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells.

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第一作者： Kathrin,Hammon

第一单位： Department of Internal Medicine III, University Hospital Regensburg; Regensburg, Germany; LIT - Leibniz Institute for Immunotherapy; Regensburg.

作者： Kathrin,Hammon ^[1] ; Kathrin,Renner ^[2] ; Michael,Althammer ^[3] ; Florian,Voll ^[4] ; Nathalie,Babl ^[3] ; Sonja-Maria,Decking ^[5] ; Peter J,Siska ^[3] ; Carina,Matos ^[3] ; Zugey Elizabeth Cárdenas,Conejo ^[3] ; Karina,Mendes ^[6] ; Friederike,Einwag ^[3] ; Heiko,Siegmund ^[7] ; Sabine,Iberl ^[3] ; Raffaela S,Berger ^[8] ; Katja,Dettmer ^[8] ; Rebecca,Schoenmehl ^[9] ; Christoph,Brochhausen ^[10] ; Wolfgang,Herr ^[3] ; Peter J,Oefner ^[8] ; Michael,Rehli ^[1] ; Simone,Thomas ^[1] ; Marina,Kreutz ^[11]

作者单位： Department of Internal Medicine III, University Hospital Regensburg; Regensburg, Germany; LIT - Leibniz Institute for Immunotherapy; Regensburg. ^[1] Department of Internal Medicine III, University Hospital Regensburg; Regensburg, Germany; LIT - Leibniz Institute for Immunotherapy; Regensburg, Germany; Department of Otorhinolaryngology, University Hospital Regensburg, Regensburg. ^[2] Department of Internal Medicine III, University Hospital Regensburg; Regensburg. ^[3] LIT - Leibniz Institute for Immunotherapy; Regensburg. ^[4] Department of Otorhinolaryngology, University Hospital Regensburg, Regensburg. ^[5] Department of Internal Medicine III, University Hospital Regensburg; Regensburg, Germany; Present address: Universidade Católica Portuguesa, Center for Interdisciplinary Research in Health (CIIS), Institute of Health Sciences (ICS); Viseu. ^[6] Institute of Pathology, University of Regensburg; Regensburg. ^[7] Institute of Functional Genomics, University of Regensburg; Regensburg. ^[8] Institute of Pathology, University Medical Center Mannheim, University Heidelberg, Mannheim. ^[9] Institute of Pathology, University of Regensburg; Regensburg, Germany; Institute of Pathology, University Medical Center Mannheim, University Heidelberg, Mannheim. ^[10] Department of Internal Medicine III, University Hospital Regensburg; Regensburg, Germany; LIT - Leibniz Institute for Immunotherapy; Regensburg. marina.kreutz@ukr.de. ^[11]