METTL3 drives NSCLC metastasis by enhancing CYP19A1 translation and oestrogen synthesis.

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第一作者： Wangyang,Meng

第一单位： Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

作者： Wangyang,Meng ^[1] ; Han,Xiao ^[2] ; Rong,Zhao ^[3] ; Jiaping,Chen ^[2] ; Yangwei,Wang ^[4] ; Peiyuan,Mei ^[2] ; Hecheng,Li ^[2] ; Yongde,Liao ^[5]

作者单位： Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. ^[1] Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. ^[2] Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China. sinohanx@hust.edu.cn. ^[3] Department of Cardiothoracic Surgery, Third Affiliated Hospital of Kunming Medical University (Yunnan Cancer Hospital), Kunming, Yunnan, China. ^[4] Department of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. lihecheng2000@hotmail.com. ^[5] Department of Thoracic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. liaoyongde@hust.edu.cn. ^[6]

关键词 Estrogen METTL3 NSCLC Small molecule inhibitor Translation regulation

DOI 10.1186/s13578-024-01194-9

PMID 38238831

发布时间 2024-01-21

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