LINC MIR503HG Controls SC-β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1.

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作者： Yang,Xu ^[1] ; Susu,Mao ^[2] ; Haowen,Fan ^[3] ; Jian,Wan ^[4] ; Lin,Wang ^[1] ; Mingyu,Zhang ^[3] ; Shajun,Zhu ^[1] ; Jin,Yuan ^[3] ; Yuhua,Lu ^[1] ; Zhiwei,Wang ^[5] ; Bin,Yu ^[6] ; Zhaoyan,Jiang ^[1] ; Yan,Huang ^[7]

作者单位： Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China. ^[1] Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, School of Medicine, Tongji University, Shanghai, 200092, China. ^[2] Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China. ^[3] Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, 226001, China. ^[4] Department of Graduate School, Dalian Medical University, Dalian, Liaoning, 116000, China. ^[5] Department of Nuclear Medicine, Beijing Friendship Hospital, Affiliated to Capital Medical University, Beijing, 100050, China. ^[6] Department of Endocrinology and Metabolism, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China. ^[7]

关键词 differentiation human pluripotent stem cells lncRNA pancreatic progenitors scRNA‐seq

主题词人类(Humans);抗原, CD(Antigens, CD);钙黏着糖蛋白类(Cadherins);细胞分化(Cell Differentiation);糖尿病(Diabetes Mellitus);同源盒结构域蛋白质类(Homeodomain Proteins);胰岛素(Insulin);反式激活因子类(Trans-Activators);转录因子(Transcription Factors);胰岛素分泌细胞(Insulin-Secreting Cells)

DOI 10.1002/advs.202305631

PMID 38243869

发布时间 2024-04-15

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2024年11卷13期

e2305631页

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LINC MIR503HG Controls SC-β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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LINC MIR503HG Controls SC-β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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