NanoSHP099-Targeted SHP2 Inhibition Boosts Ly6C<sup>low</sup> Monocytes/Macrophages Differentiation to Accelerate Thrombolysis.

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作者： Kejing,Ying ^[1] ; Wanghao,Xin ^[1] ; Yiming,Xu ^[1] ; Dandan,Lv ^[1] ; Huiqi,Zhu ^[1] ; Yeping,Li ^[1] ; Wangting,Xu ^[2] ; Chao,Yan ^[3] ; Yiqing,Li ^[1] ; Hongqiang,Cheng ^[4] ; Enguo,Chen ^[4] ; Guofeng,Ma ^[1] ; Xue,Zhang ^[1] ; Yuehai,Ke ^[3]

作者单位： Department of Pulmonary and Critical Care Medicine, Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310016, China. ^[1] Department of Respiratory, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China. ^[2] Department of Pathology and Pathophysiology, and Department of Respiratory Medicine at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China. ^[3] Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China. ^[4]

关键词 Liposomes Ly6Clow monocytes/macrophages SHP099 collagenolysis thrombolysis

主题词动物(Animals);小鼠(Mice);白细胞(Leukocytes);巨噬细胞(Macrophages);单核细胞(Monocytes);血栓溶解疗法(Thrombolytic Therapy);血栓形成(Thrombosis);哌啶类(Piperidines);嘧啶类(Pyrimidines);蛋白质酪氨酸磷酸酶, 非受体11型(Protein Tyrosine Phosphatase, Non-Receptor Type 11)

DOI 10.1002/advs.202308166

PMID 38247197

发布时间 2024-04-15

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2024年11卷13期

e2308166页

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NanoSHP099-Targeted SHP2 Inhibition Boosts Ly6C<sup>low</sup> Monocytes/Macrophages Differentiation to Accelerate Thrombolysis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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NanoSHP099-Targeted SHP2 Inhibition Boosts Ly6C<sup>low</sup> Monocytes/Macrophages Differentiation to Accelerate Thrombolysis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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