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NfL reliability across laboratories, stage-dependent diagnostic performance and matrix comparability in genetic FTD: a large GENFI study.

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第一作者: Christoph,Linnemann
第一单位: Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany matthis.synofzik@uni-tuebingen.de christoph.linnemann@upk.ch.;Center of Old Age Psychiatry, Psychiatric University Hospital (UPK), University of Basel, Basel, Switzerland.
作者单位: Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany matthis.synofzik@uni-tuebingen.de christoph.linnemann@upk.ch.;Center of Old Age Psychiatry, Psychiatric University Hospital (UPK), University of Basel, Basel, Switzerland. [1] Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.;Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. [2] UK Dementia Research Institute at UCL, London, UK.;Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden. [3] UK Dementia Research Institute at UCL, London, UK.;Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK. [4] Neurologic Clinic and Policlinic, MS Center and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel, Switzerland. [5] Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK. [6] Department of Neurology, Erasmus Medical Centre, Rotterdam, Netherlands. [7] Cognitive Disorders Unit, Department of Neurology, Donostia Universitary Hospital, San Sebastian, Spain.;Biodonostia Health Research Institute, Neuroscience Area, San Sebastian, Spain. [8] Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. [9] Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d'Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona, Barcelona, Spain. [10] IRCCS Ospedale Policlinico, Fondazione Ca' Granda, Milan, Italy.;Centro Dino Ferrari, University of Milan, Milan, Italy. [11] Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval, Québec, Alberta, Canada. [12] Center for Alzheimer Research, Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Bioclinicum, Karolinska Institutet, Solna, Sweden.;Unit for Hereditary Dementias, Theme Aging, Karolinska University Hospital, Solna, Sweden. [13] Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada. [14] Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada. [15] Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. [16] Department of Clinical Neurological Sciences, University of Western Ontario, London, Ontario, Canada. [17] Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven, Belgium.;Neurology Service, University Hospitals Leuven, Leuven, Belgium. [18] Faculty of Medicine, University of Lisbon, Lisbon, Portugal. [19] Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford, UK.;Department of Brain Sciences, Imperial College, London, UK. [20] Division of Neuroscience and Experimental Psychology, Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK.;Department of Geriatric Medicine, Klinikum Hochsauerland, Arnsberg, Germany. [21] Department of Psychiatry, McGill University Health Centre, McGill University, Montreal, Québec, Canada.;McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Québec, Canada. [22] Sorbonne Université, Paris Brain Institute - Institut du Cerveau - ICM, Inserm U1127, CNRS UMR 7225, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France.;Centre de référence des démences rares ou précoces, IM2A, Département de Neurologie, AP-HP, Hôpital Pitié-Salpêtrière, Paris, France. [23] Istituto Neurologico Carlo Besta, Fondazione IRCCS, Milan, Italy. [24] Neurology Service, Faculty of Medicine, University Hospital of Coimbra (HUC), University of Coimbra, Coimbra, Portugal.;Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal. [25] University of Lille, Lille, France.;Inserm 1172, Lille, France. [26] Department of Neurology, Ludwig-Maximilians Universität München, Munich, Germany.;German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. [27] Department of Neurology, University of Ulm, Ulm, Germany. [28] Department of Neurofarba, University of Florence, Firenze, Italy.;Don Carlo Gnocchi, IRCCS Fondazione, Firenze, Italy. [29] Division Translational Genomics of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany matthis.synofzik@uni-tuebingen.de christoph.linnemann@upk.ch.;Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. [30]
DOI 10.1136/jnnp-2023-332464
PMID 38253362
发布时间 2025-05-30
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Journal of neurology, neurosurgery, and psychiatry

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