Targeted Proteomics Reveals Quantitative Differences in Low-Abundance Glycosyltransferases of Patients with Congenital Disorders of Glycosylation.

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第一作者： Roman,Sakson

第一单位： Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany.;Heidelberg Biosciences International Graduate School (HBIGS), Heidelberg University, 69120 Heidelberg, Germany.

作者： Roman,Sakson ^[1] ; Lars,Beedgen ^[2] ; Patrick,Bernhard ^[3] ; K Merve,Alp ^[4] ; Nicole,Lübbehusen ^[5] ; Ralph,Röth ^[6] ; Beate,Niesler ^[7] ; Marcin,Luzarowski ^[5] ; Olga,Shevchuk ^[8] ; Matthias P,Mayer ^[5] ; Christian,Thiel ^[2] ; Thomas,Ruppert ^[5]

作者单位： Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany.;Heidelberg Biosciences International Graduate School (HBIGS), Heidelberg University, 69120 Heidelberg, Germany. ^[1] Center for Child and Adolescent Medicine, Department Pediatrics I, Heidelberg University, 69120 Heidelberg, Germany. ^[2] Institute for Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany. ^[3] Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany. ^[4] Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Alliance, 69120 Heidelberg, Germany. ^[5] nCounter Core Facility, Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany. ^[6] nCounter Core Facility, Institute of Human Genetics, University Hospital Heidelberg, 69120 Heidelberg, Germany.;Interdisciplinary Center for Neurosciences, Heidelberg University, 69120 Heidelberg, Germany. ^[7] Department of Immunodynamics, Institute of Experimental Immunology and Imaging, University Hospital Essen, 45147 Essen, Germany. ^[8]

关键词 MRM Skyline congenital disorders of glycosylation endoplasmic reticulum glycosylation nCounter proteomics