Major vault protein regulates tumor-associated macrophage polarization through interaction with signal transducer and activator of transcription 6.

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作者： Chen,Yu ^[1] ; Qingmei,Zhu ^[1] ; Caijiao,Ma ^[1] ; Chuanjin,Luo ^[1] ; Longyu,Nie ^[1] ; Huanhuan,Cai ^[2] ; Qiming,Wang ^[3] ; Fubing,Wang ^[4] ; Hong,Ren ^[5] ; Huan,Yan ^[1] ; Ke,Xu ^[1] ; Li,Zhou ^[1] ; Caiyan,Zhang ^[5] ; Guoping,Lu ^[5] ; Zhibing,Lu ^[2] ; Ying,Zhu ^[1] ; Shi,Liu ^[6]

作者单位： State Key Laboratory of Virology, Modern Virology Research Center, Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, China. ^[1] Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.;Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan, China. ^[2] College of Bioscience and Biotechnology, Hunan Agricultural University, Hunan, Changsha, China. ^[3] Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China. ^[4] Shanghai Children's Medical Center, Affiliated Hospital to Shanghai Jiao Tong University School of Medicine, Shanghai, China. ^[5] State Key Laboratory of Virology, Modern Virology Research Center, Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, China.;Institute of Myocardial Injury and Repair, Wuhan University, Wuhan, China.;College of Bioscience and Biotechnology, Hunan Agricultural University, Hunan, Changsha, China.;Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China. ^[6]

关键词 HCC MVP STAT6 TAMs TME polarization

主题词人类(Humans);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);STAT6转录因子(STAT6 Transcription Factor);肿瘤微环境(Tumor Microenvironment);穹窿核糖核蛋白颗粒(Vault Ribonucleoprotein Particles)

DOI 10.3389/fimmu.2023.1289795

PMID 38264642

发布时间 2024-10-23

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Frontiers in immunology

2023年14卷

1289795页

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Major vault protein regulates tumor-associated macrophage polarization through interaction with signal transducer and activator of transcription 6.

Frontiers in immunology

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Frontiers in immunology

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Major vault protein regulates tumor-associated macrophage polarization through interaction with signal transducer and activator of transcription 6.

Frontiers in immunology

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Frontiers in immunology

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