Evaluating in vivo effectiveness of sotrovimab for the treatment of Omicron subvariant BA.2 versus BA.1: a multicentre, retrospective cohort study.

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第一作者： Carson K L,Lo

第一单位： Division of Infectious Diseases, Department of Medicine, McMaster University, Hamilton, ON, Canada. carson.lo@medportal.ca.

作者： Carson K L,Lo ^[1] ; Calvin K F,Lo ^[2] ; Adam S,Komorowski ^[3] ; Victor,Leung ^[4] ; Nancy,Matic ^[5] ; Susan,McKenna ^[3] ; Santiago,Perez-Patrigeon ^[6] ; Prameet M,Sheth ^[3] ; Christopher F,Lowe ^[6] ; Zain,Chagla ^[7] ; Anthony D,Bai ^[8]

作者单位： Division of Infectious Diseases, Department of Medicine, McMaster University, Hamilton, ON, Canada. carson.lo@medportal.ca. ^[1] Transplant Infectious Diseases and Ajmera Transplant Centre, University Health Network, 585 University Avenue, MaRS Building, 9th Floor, Toronto, ON, M5G 2N2, Canada. carson.lo@medportal.ca. ^[2] Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. ^[3] Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada. ^[4] Medical Microbiology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. ^[5] Division of Medical Microbiology and Virology, St. Paul's Hospital, Providence Health Care, Vancouver, BC, Canada. ^[6] Department of Pharmacy Services, Kingston Health Sciences Centre, Kingston, ON, Canada. ^[7] Division of Infectious Diseases, Department of Medicine, Queen's University, Kingston, ON, Canada. ^[8] Division of Microbiology, Kingston Health Sciences Centre, Kingston, ON, Canada. ^[9] Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada. ^[10] Department of Biomedical & Molecular Sciences, Queen's University, Kingston, ON, Canada. ^[11] Gastrointestinal Disease Research Unit, Kingston Health Sciences Centre, Kingston, ON, Canada. ^[12] Division of Infectious Diseases, Department of Medicine, McMaster University, Hamilton, ON, Canada. ^[13] St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada. ^[14]

关键词 Antibodies, Monoclonal BA.2 subvariant COVID-19 COVID-19 drug treatment Omicron SARS-CoV-2 Sotrovimab

主题词人类(Humans);回顾性研究(Retrospective Studies);加拿大(Canada);抗体, 中和(Antibodies, Neutralizing)

DOI 10.1186/s13104-024-06695-x

PMID 38267971

发布时间 2024-01-27

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准确一般字义偏差语意偏离译文作用小提交