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Phase 1 trial of navitoclax and sorafenib in patients with relapsed or refractory solid tumors with hepatocellular carcinoma expansion cohort.

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作者单位: Division of Medical Oncology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. [1] Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA. [2] Department of Molecular Pharmacology and Experimental Therapeutics (MPET), Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. [3] Department of Hematology and Oncology, Mayo Clinic, 5881 E. Mayo Blvd., Phoenix, AZ, 85054, USA. [4] Department of Hematology & Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. [5] Department of Hematology/Oncology, Fox Chase Cancer Center, Lewis Katz School of Medicine, Philadelphia, PA, 19111, USA. [6] Division of Hematology/Oncology, University of Maryland School of Medicine, 22 S. Greene Street, Baltimore, MD, 21201, USA. [7] Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [8] Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA, 19107, USA. [9] University of Colorado Cancer Center - Anschutz Medical Campus, 1665 Aurora Ct, Aurora, CO, 80045, USA. [10] Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. [11] Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute, Bethesda, MD, 20892, USA. [12] Case Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA. [13] Taussig Cancer Center, Cleveland Clinic, Cleveland, OH, 44195, USA. [14] Division of Medical Oncology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. costello.brian@mayo.edu. [15]
DOI 10.1007/s10637-024-01420-8
PMID 38270822
发布时间 2024-05-07
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