Blood FOLR3 methylation dysregulations and heterogeneity in non-small lung cancer highlight its strong associations with lung squamous carcinoma.

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第一作者： Yunhui,Qu

第一单位： Department of Clinical Laboratory, the First Affiliated Hospital of Zhengzhou University and the Key Clinical Laboratory of Henan Province, Zhengzhou, 450052, China.

作者： Yunhui,Qu ^[1] ; Xiuzhi,Zhang ^[2] ; Rong,Qiao ^[3] ; Feifei,Di ^[4] ; Yakang,Song ^[4] ; Jun,Wang ^[4] ; Longtao,Ji ^[5] ; Jie,Zhang ^[6] ; Wanjian,Gu ^[6] ; Yifei,Fang ^[7] ; Baohui,Han ^[3] ; Rongxi,Yang ^[8] ; Liping,Dai ^[9] ; Songyun,Ouyang ^[10]

作者单位： Department of Clinical Laboratory, the First Affiliated Hospital of Zhengzhou University and the Key Clinical Laboratory of Henan Province, Zhengzhou, 450052, China. ^[1] Department of Epidemiology, School of Public Health, Zhengzhou University, Zhengzhou, 4500001, China. ^[2] Department of Pulmonary Medicine, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, 200030, China. ^[3] Nanjing TANTICA Biotechnology Co. Ltd, Nanjing, 210000, China. ^[4] Henan Institute of Medical and Pharmaceutical Sciences & Henan Key Medical Laboratory of Tumor Molecular Biomarkers, Zhengzhou University, Zhengzhou, 450052, China. ^[5] Department of Clinical Laboratory, Jiangsu Province Hospital of Chinese Medicine, Nanjing, 210000, China. ^[6] Department of Respiratory and Sleep Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ^[7] Nanjing TANTICA Biotechnology Co. Ltd, Nanjing, 210000, China. rongxiyang@njmu.edu.cn.;Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, 210000, China. rongxiyang@njmu.edu.cn. ^[8] Henan Institute of Medical and Pharmaceutical Sciences & Henan Key Medical Laboratory of Tumor Molecular Biomarkers, Zhengzhou University, Zhengzhou, 450052, China. lpdai@zzu.edu.cn. ^[9] Department of Respiratory and Sleep Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ouyangsy@163.com. ^[10]

关键词 DNA methylation Early detection FOLR3 Lung cancer Mass spectrometry

主题词人类(Humans);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);癌, 鳞状细胞(Carcinoma, Squamous Cell);DNA甲基化(DNA Methylation);肺(Lung);肺肿瘤(Lung Neoplasms)

DOI 10.1186/s12931-024-02691-8

PMID 38273401

发布时间 2024-10-23

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