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Discovery of proqodine A derivatives with antitumor activity targeting NAD(P)H: quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase.

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第一作者： Jiangzhou,Song

第一单位： State Key Laboratory of Natural Medicines, Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China.

作者： Jiangzhou,Song ^[1] ; Guiqing,Zou ^[2] ; Zhou,Zhao ^[1] ; Ya,Zhu ^[1] ; Jiayu,Xue ^[1] ; Lanjia,Ao ^[1] ; Huiyong,Sun ^[1] ; Haiping,Hao ^[3] ; Bo,Zhang ^[4] ; Xiaowei,Xu ^[5]

作者单位： State Key Laboratory of Natural Medicines, Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China. ^[1] State Key Laboratory of Natural Medicines, Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China. ^[2] State Key Laboratory of Natural Medicines, Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China. Electronic address: haipinghao@cpu.edu.cn. ^[3] State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China. Electronic address: zb3981444@cpu.edu.cn. ^[4] State Key Laboratory of Natural Medicines, Key Lab of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, China. Electronic address: xw@cpu.edu.cn. ^[5]

关键词 NAD(+)NAMPT NQO1 ROS T8

医学主题词人类(Humans);NAD(NAD);细胞系, 肿瘤(Cell Line, Tumor);活性氧(Reactive Oxygen Species);烟酰胺磷酸核糖基转移酶(Nicotinamide Phosphoribosyltransferase);细胞因子类(Cytokines);醌类(Quinones);氧化还原酶类(Oxidoreductases)

DOI 10.1016/S1875-5364(24)60564-9

PMID 38278561

发布时间 2024-02-06

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Chinese journal of natural medicines

2024年22卷1期

75-88页

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Chinese journal of natural medicines

2024年22卷1期

75-88页

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Discovery of proqodine A derivatives with antitumor activity targeting NAD(P)H: quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase.

Chinese journal of natural medicines

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Chinese journal of natural medicines

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Discovery of proqodine A derivatives with antitumor activity targeting NAD(P)H: quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase.

Chinese journal of natural medicines

相似文献

同项目论文

Chinese journal of natural medicines

相关期刊

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