SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

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作者： Huixia,Zhang ^[1] ; Shasha,Li ^[1] ; Runxin,Zhou ^[2] ; Tianqi,Dong ^[1] ; Xiao,Zhang ^[1] ; Man,Yu ^[1] ; Jiaming,Lin ^[1] ; Mingjun,Shi ^[1] ; Ershuo,Geng ^[1] ; Juebei,Li ^[1] ; Mingwei,Wang ^[3] ; Liu,Huang ^[4] ; Xiang-Ping,Yang ^[5] ; Shuguo,Sun ^[6]

作者单位： Department of Human Anatomy, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, China. ^[1] Department of Biochemistry and Molecular Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, China. ^[2] Department of Pathology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, China. ^[3] Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jie Fang Avenue, Wuhan, 430030, China. ^[4] Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, China. ^[5] Department of Human Anatomy, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, China; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, 430030, China. Electronic address: shuguo@hust.edu.cn. ^[6]

关键词 Hippo pathway Lung cancer Oncogenic transcription SRCAP YAP/TAZ