首页> Angiogenesis> Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors.

Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors.

导出 OA

翻译打印收藏纠错

第一作者： T,Al Tabosh

第一单位： Biosanté unit U1292, Grenoble Alpes University, INSERM, CEA, 38000, Grenoble, France.

作者： T,Al Tabosh ^[1] ; H,Liu ^[1] ; D,Koça ^[1] ; M,Al Tarrass ^[1] ; L,Tu ^[2] ; S,Giraud ^[3] ; L,Delagrange ^[4] ; M,Beaudoin ^[4] ; S,Rivière ^[5] ; V,Grobost ^[6] ; M,Rondeau-Lutz ^[7] ; O,Dupuis ^[8] ; N,Ricard ^[1] ; E,Tillet ^[1] ; P,Machillot ^[1] ; A,Salomon ^[1] ; C,Picart ^[1] ; C,Battail ^[1] ; S,Dupuis-Girod ^[9] ; C,Guignabert ^[2] ; A,Desroches-Castan ^[1] ; S,Bailly ^[10]

作者单位： Biosanté unit U1292, Grenoble Alpes University, INSERM, CEA, 38000, Grenoble, France. ^[1] Faculté de Médecine, Pulmonary Hypertension: Pathophysiology and Novel Therapies, Université Paris-Saclay, 94276, Le Kremlin-Bicêtre, France.;INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies», Hôpital Marie Lannelongue, 92350, Le Plessis-Robinson, France. ^[2] Genetics Department, Femme-Mère-Enfants Hospital, Hospices Civils de Lyon, 69677, Bron, France. ^[3] Genetics Department, Femme-Mère-Enfants Hospital, Hospices Civils de Lyon, 69677, Bron, France.;National Reference Center for HHT, 69677, Bron, France. ^[4] Internal Medicine Department, CHU of Montpellier, St Eloi Hospital and Center of Clinical Investigation, INSERM, CIC 1411, 34295, Montpellier Cedex 7, France. ^[5] Internal Medicine Department, CHU Estaing, 63100, Clermont-Ferrand, France. ^[6] Internal Medicine Department, University Hospital of Strasbourg, 67091, Strasbourg Cedex, France. ^[7] Hôpital Lyon SUD, Hospices Civils de Lyon, Université Claude Bernard Lyon 1, 69100, Villeurbanne, France.;Faculty of Medicine, Lyon University, 69921, Lyon, France. ^[8] Biosanté unit U1292, Grenoble Alpes University, INSERM, CEA, 38000, Grenoble, France.;Genetics Department, Femme-Mère-Enfants Hospital, Hospices Civils de Lyon, 69677, Bron, France.;National Reference Center for HHT, 69677, Bron, France. ^[9] Biosanté unit U1292, Grenoble Alpes University, INSERM, CEA, 38000, Grenoble, France. sabine.bailly@cea.fr. ^[10]

关键词 ALK1 BMP HHT LFNG PAH RNA-seq