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Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: In vitro and in silico studies.

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第一作者： Ibrahim H,Eissa

第一单位： Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, 11884, Egypt.

作者： Ibrahim H,Eissa ^[1] ; Hazem,Elkady ^[1] ; Mahmoud,Rashed ^[1] ; Alaa,Elwan ^[1] ; Mohamed,Hagras ^[2] ; Mohammed A,Dahab ^[1] ; Mohammed S,Taghour ^[1] ; Ibrahim M,Ibrahim ^[3] ; Dalal Z,Husein ^[4] ; Eslam B,Elkaeed ^[5] ; Hanan A,Al-Ghulikah ^[6] ; Ahmed M,Metwaly ^[7] ; Hazem A,Mahdy ^[1]

作者单位： Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, 11884, Egypt. ^[1] Department of Pharmaceutical Organic Chemistry, College of Pharmacy, Al-Azhar University, Cairo, 11884, Egypt. ^[2] Biophysics Department, Faculty of Science, Cairo University, Giza, 12613, Egypt. ^[3] Chemistry Department, Faculty of Science, New Valley University, El-Kharja, 72511, Egypt. ^[4] Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, 13713, Saudi Arabia. ^[5] Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. ^[6] Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, 11884, Egypt. ^[7]

关键词 Anticancer Drug design In silico studies Thiazolidine-2,4-dione VEGFR-2 inhibitors

DOI 10.1016/j.heliyon.2024.e24005

PMID 38298627

发布时间 2024-10-23

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Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: <i>In vitro</i> and <i>in silico</i> studies.

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Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: <i>In vitro</i> and <i>in silico</i> studies.

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