Self-Disassembling and Oxygen-Generating Porphyrin-Lipoprotein Nanoparticle for Targeted Glioblastoma Resection and Enhanced Photodynamic Therapy.

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作者： Yaoxing,Chen ^[1] ; Yuxiao,Ma ^[2] ; Kexin,Shi ^[1] ; Huan,Chen ^[1] ; Xiao,Han ^[1] ; Chenxuan,Wei ^[1] ; Yingqi,Lyu ^[1] ; Yukun,Huang ^[1] ; Renhe,Yu ^[1] ; Yun,Song ^[3] ; Qingxiang,Song ^[1] ; Jiyao,Jiang ^[2] ; Junfeng,Feng ^[2] ; Yingying,Lin ^[2] ; Jun,Chen ^[4] ; Hongzhuan,Chen ^[1] ; Gang,Zheng ^[5] ; Xiaoling,Gao ^[1] ; Gan,Jiang ^[6]

作者单位： Department of Pharmacology and Chemical Biology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Universities Collaborative Innovation Center for Translational Medicine, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, China. ^[1] Brain Injury Centre, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 1630 Dongfang Road, Shanghai, 200127, China. ^[2] Department of Pharmacy, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Shanghai, 200040, China. ^[3] Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai, 201203, China. ^[4] Institute of Interdisciplinary Integrative Biomedical Research, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201210, China. ^[5] Department of Medical Biophysics, University of Toronto, 101 College Street, Toronto, Ontario, M5G 1L7, Canada. ^[6]

关键词 calcium peroxide enhanced photodynamic therapy fluorescence‐guided surgery glioblastoma‐initiating cells macropinocytosis porphyrin lipoprotein nanoparticles