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Meta-analysis of ACE inhibitor-induced angioedema identifies novel risk locus.

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第一作者: Carina M,Mathey
第一单位: Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany.
作者单位: Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany. [1] Institute for Genomic Statistics and Bioinformatics, University Hospital Bonn, Bonn, Germany; Centre for Human Genetics, University of Marburg, Marburg, Germany. [2] Uppsala Clinical Research Center, Uppsala, Sweden; Department of Medical Sciences, Clinical Pharmacogenomics and Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [3] Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia. [4] Icahn School of Medicine, Mount Sinai, New York, NY. [5] Department of Dermatology and Allergy, Comprehensive Allergy Center, Hannover Medical School, Hannover, Germany. [6] Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Krems, Austria. [7] Department of Dermatology, SLK Hospital Heilbronn, Heilbronn, Germany. [8] Department of Dermatology and Venereology, Medical University Graz, Graz, Austria. [9] Department of Dermatology, Venereology and Allergology, St Josef Hospital, University Medical Center, Ruhr University Bochum, Bochum, Germany. [10] Department of Dermatology, Venereology and Allergology, St Josef Hospital, University Medical Center, Ruhr University Bochum, Bochum, Germany; Institute of Health Care Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [11] Department of Dermatology and Allergy, University Hospital of Bonn, Bonn, Germany. [12] Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany. [13] Department of Otorhinolaryngology-Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany. [14] Department of Dermatology and Allergy, Aachen Comprehensive Allergy Center, University Hospital RWTH Aachen, Aachen, Germany. [15] Department for Children and Adolescents, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt, Germany. [16] Research Division, Federal Institute for Drugs and Medical Devices, Bonn, Germany. [17] Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany. [18] Molecular Diagnostics and Clinical Research Unit, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark. [19] Molecular Diagnostics and Clinical Research Unit, Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark; OPEN, University of Southern Denmark, Odense, Denmark. [20] National Research Centre for the Working Environment, Copenhagen, Denmark. [21] Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [22] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC. [23] Department of Clinical Institute, University of Southern Denmark, Odense, Denmark; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark. [24] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [25] Department of Otorhinolaryngology-Head and Neck Surgery and Audiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. [26] Department of Medical Sciences, Clinical Pharmacogenomics and Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [27] Department of Clinical Immunology, Copenhagen Hospital Biobank Unit, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [28] Department of Clinical Immunology, Copenhagen Hospital Biobank Unit, Rigshospitalet, Copenhagen, Denmark. [29] Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [30] Statens Serum Institute, Copenhagen, Denmark. [31] Departments of Clinical Immunology, Aarhus University, Aarhus, Denmark; Departments of Clinical Medicine, Aarhus University, Aarhus, Denmark. [32] Department of Otorhinolaryngology-Head and Neck Surgery and Audiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Departments of Private Practice Ølsemaglevej, Køge, Denmark. [33] Laboratory for Molecular Cardiology, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; Laboratory for Molecular Cardiology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark. [34] Department of Dermatology and Allergy, Aachen Comprehensive Allergy Center, University Hospital RWTH Aachen, Aachen, Germany; Research Division, Federal Institute for Drugs and Medical Devices, Bonn, Germany. [35] Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital Bonn, Bonn, Germany; Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Jülich, Germany. Electronic address: forstner@uni-bonn.de. [36]
DOI 10.1016/j.jaci.2023.11.921
PMID 38300190
发布时间 2024-04-08
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