CRISPR-Cas12a-based colorimetric aptasensor for aflatoxin M1 detection based on oxidase-mimicking activity of flower-like MnO<sub>2</sub> nanozymes.

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第一作者： Masoomeh,Esmaelpourfarkhani

第一单位： Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

作者： Masoomeh,Esmaelpourfarkhani ^[1] ; Mohammad,Ramezani ^[2] ; Mona,Alibolandi ^[2] ; Khalil,Abnous ^[3] ; Seyed Mohammad,Taghdisi ^[4]

作者单位： Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. ^[1] Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. ^[2] Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: abnouskh@mums.ac.ir. ^[3] Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: taghdisihm@mums.ac.ir. ^[4]

关键词 Aflatoxin M1 CRISPR-Cas12a Colorimetric aptasensor MnO2 nanoflower Oxidase-like activity

主题词黄曲霉毒素M1(Aflatoxin M1);氧化还原酶类(Oxidoreductases);比色法(Colorimetry);锰化合物(Manganese Compounds);生物传感技术(Biosensing Techniques);氧化物(Oxides)

DOI 10.1016/j.talanta.2024.125729

PMID 38306811

发布时间 2024-02-26

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