首页> The lancet. HIV> Safety of teropavimab and zinlirvimab with lenacapavir once every 6 months for HIV treatment: a phase 1b, randomised, proof-of-concept study.

Safety of teropavimab and zinlirvimab with lenacapavir once every 6 months for HIV treatment: a phase 1b, randomised, proof-of-concept study.

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第一作者： Joseph J,Eron

第一单位： Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA.

作者： Joseph J,Eron ^[1] ; Susan J,Little ^[2] ; Gordon,Crofoot ^[3] ; Paul,Cook ^[4] ; Peter J,Ruane ^[5] ; Dushyantha,Jayaweera ^[6] ; Laurie A,VanderVeen ^[7] ; Edwin,DeJesus ^[8] ; Yanan,Zheng ^[9] ; Anthony,Mills ^[10] ; Hailin,Huang ^[11] ; Sarah E,Waldman ^[12] ; Moti,Ramgopal ^[13] ; Linda,Gorgos ^[14] ; Sean E,Collins ^[15] ; Jared M,Baeten ^[16] ; Marina,Caskey ^[17]

作者单位： Division of Infectious Diseases, University of North Carolina, Chapel Hill, NC, USA. ^[1] Division of Infectious Diseases, University of California, San Diego, CA, USA. ^[2] Crofoot Research Center, Houston, TX, USA. ^[3] Division of Infectious Diseases, East Carolina University, Greenville, NC, USA. ^[4] Ruane Clinical Research, Los Angeles, CA, USA. ^[5] Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL, USA. ^[6] Clinical Virology, Gilead Sciences, Foster City, CA, USA. ^[7] Orlando Immunology Center, Orlando, FL, USA. ^[8] Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA. ^[9] Men's Health Foundation, Los Angeles, CA, USA. ^[10] Biostatistics, Gilead Sciences, Foster City, CA, USA. ^[11] Division of Infectious Diseases, University of California, Davis, Sacramento, CA, USA. ^[12] Midway Immunology and Research Center, Fort Pierce, FL, USA. ^[13] AXCES Research Group, Santa Fe, NM, USA. ^[14] Clinical Development, Gilead Sciences, Foster City, CA, USA. Electronic address: sean.collins@gilead.com. ^[15] Clinical Development, Gilead Sciences, Foster City, CA, USA. ^[16] Laboratory of Molecular Immunology, Rockefeller University, New York, NY, USA. ^[17]

医学主题词成年人(Adult);人类(Humans);男(雄)性(Male);女(雌)性(Female);HIV感染(HIV Infections);抗HIV药(Anti-HIV Agents);HIV抗体(HIV Antibodies);RNA(RNA);HIV-1(HIV-1);病毒载量(Viral Load)

DOI 10.1016/S2352-3018(23)00293-X

PMID 38307098

发布时间 2026-03-17

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The lancet. HIV

2024年11卷3期

e146-e155页

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The lancet. HIV

2024年11卷3期

e146-e155页

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Safety of teropavimab and zinlirvimab with lenacapavir once every 6 months for HIV treatment: a phase 1b, randomised, proof-of-concept study.

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Safety of teropavimab and zinlirvimab with lenacapavir once every 6 months for HIV treatment: a phase 1b, randomised, proof-of-concept study.

The lancet. HIV

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