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首页> Trials> A multicenter double-blind randomized crossover study comparing the impact of dorsal subthalamic nucleus deep brain stimulation versus standard care on apathy in Parkinson's disease: a study protocol.

A multicenter double-blind randomized crossover study comparing the impact of dorsal subthalamic nucleus deep brain stimulation versus standard care on apathy in Parkinson's disease: a study protocol.

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作者： T J C,Zoon ^[1] ; G,van Rooijen ^[2] ; M F,Contarino ^[3] ; S,van der Gaag ^[3] ; R,Zutt ^[3] ; J T,van Asseldonk ^[4] ; P,van den Munckhof ^[5] ; P R,Schuurman ^[5] ; D A J P,Denys ^[2] ; R M A,de Bie ^[6]

作者单位： Department of Psychiatry, Amsterdam UMC, Location AMC, Amsterdam, the Netherlands. t.j.zoon@amsterdamumc.nl. ^[1] Department of Psychiatry, Amsterdam UMC, Location AMC, Amsterdam, the Netherlands. ^[2] HagaZiekenhuis, the Hague, the Netherlands. ^[3] Elisabeth-TweeSteden Ziekenhuis, Tilburg, the Netherlands. ^[4] Department of Neurosurgery, Amsterdam UMC, Amsterdam, the Netherlands. ^[5] Department of Neurology, Amsterdam UMC, Location AMC, Amsterdam, the Netherlands. ^[6]

关键词 Apathy Deep brain stimulation Neurology Parkinson’s disease Randomized controlled trial

主题词人类(Humans);帕金森病(Parkinson Disease);丘脑底核(Subthalamic Nucleus);情感淡漠(Apathy);交叉研究(Cross-Over Studies);深部脑刺激法(Deep Brain Stimulation);生活质量(Quality of Life);治疗结果(Treatment Outcome);随机对照试验(主题)(Randomized Controlled Trials as Topic);多中心研究(主题)(Multicenter Studies as Topic)

DOI 10.1186/s13063-024-07938-9

PMID 38308317

发布时间 2024-02-05

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2024年25卷1期

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