Discovery and Preclinical Activity of BMS-986351, an Antibody to SIRPα That Enhances Macrophage-mediated Tumor Phagocytosis When Combined with Opsonizing Antibodies.

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第一作者： Henry,Chan

第一单位： Discovery Biotherapeutics, Bristol Myers Squibb, San Diego, California.

作者： Henry,Chan ^[1] ; Christina V,Trout ^[2] ; David,Mikolon ^[1] ; Preston,Adams ^[1] ; Roberto,Guzman ^[3] ; Konstantinos,Mavrommatis ^[4] ; Mahan,Abbasian ^[5] ; Haralambos,Hadjivassiliou ^[1] ; Lawrence,Dearth ^[1] ; Brian A,Fox ^[6] ; Pallavur,Sivakumar ^[7] ; Ho,Cho ^[8] ; Kandasamy,Hariharan ^[1]

作者单位： Discovery Biotherapeutics, Bristol Myers Squibb, San Diego, California. ^[1] Strategy and Business Development, Avidity Biosciences, Inc., San Diego, California. ^[2] Takeda, San Diego, California. ^[3] Computational Genomics, Bristol Myers Squibb, San Francisco, California. ^[4] Yatiri Bio, San Diego, California. ^[5] Informatics and Predictive Sciences, Bristol Myers Squibb, Seattle, Washington. ^[6] Immuno-Oncology and Cell Therapy Discovery, Bristol Myers Squibb, Seattle, Washington. ^[7] Samsung Bioepis, Seoul, Republic of South Korea. ^[8]

主题词人类(Humans);受体, 免疫(Receptors, Immunologic);吞噬作用(Phagocytosis);巨噬细胞(Macrophages);肿瘤(Neoplasms);抗体, 肿瘤(Antibodies, Neoplasm);调理素蛋白质类(Opsonin Proteins);血液肿瘤(Hematologic Neoplasms)

DOI 10.1158/2767-9764.CRC-23-0634

PMID 38319147

发布时间 2024-03-13

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Cancer research communications

2024年4卷2期

505-515页

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Discovery and Preclinical Activity of BMS-986351, an Antibody to SIRPα That Enhances Macrophage-mediated Tumor Phagocytosis When Combined with Opsonizing Antibodies.

Cancer research communications

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Cancer research communications

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Discovery and Preclinical Activity of BMS-986351, an Antibody to SIRPα That Enhances Macrophage-mediated Tumor Phagocytosis When Combined with Opsonizing Antibodies.

Cancer research communications

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Cancer research communications

相关期刊

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