Epigenetic targets to enhance antitumor immune response through the induction of tertiary lymphoid structures.

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作者： Quadri Ajibola,Omotesho ^[1] ; Alejandro,Escamilla ^[2] ; Elisabeth,Pérez-Ruiz ^[3] ; Cecilia A,Frecha ^[4] ; Antonio,Rueda-Domínguez ^[3] ; Isabel,Barragán ^[5]

作者单位： Medical Oncology Service (Group of Translational Research in Cancer Immunotherapy and Epigenetics), Regional and Clinical University Hospitals, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Malaga, Spain.;Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. ^[1] Medical Oncology Service (Group of Translational Research in Cancer Immunotherapy and Epigenetics), Regional and Clinical University Hospitals, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Malaga, Spain.;Department of Human Physiology, Human Histology, Pathological Anatomy and Physical Sport Education, University of Malaga, Malaga, Spain. ^[2] Medical Oncology Service (Group of Translational Research in Cancer Immunotherapy and Epigenetics), Regional and Clinical University Hospitals, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Malaga, Spain. ^[3] Allergy Research Group, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Civil Hospital, Malaga, Spain. ^[4] Medical Oncology Service (Group of Translational Research in Cancer Immunotherapy and Epigenetics), Regional and Clinical University Hospitals, Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, Malaga, Spain.;Group of Pharmacoepigenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden. ^[5]

关键词 B cells CXCL13 chemokine CXCR5 biomarker epigenetics immunotherapy tertiary lymphoid structures viral vectors