Characterization of caffeine response regulatory variants in vascular endothelial cells.

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作者： Carly,Boye ^[1] ; Cynthia A,Kalita ^[1] ; Anthony S,Findley ^[1] ; Adnan,Alazizi ^[1] ; Julong,Wei ^[1] ; Xiaoquan,Wen ^[2] ; Roger,Pique-Regi ^[1] ; Francesca,Luca ^[3]

作者单位： Center for Molecular Medicine and Genetics, Wayne State University, Detroit, United States. ^[1] Department of Biostatistics, University of Michigan, Ann Arbor, United States. ^[2] Department of Obstetrics and Gynecology, Wayne State University, Detroit, United States. ^[3] Department of Biology, University of Rome Tor Vergata, Rome, Italy. ^[4]

关键词 allele-specific expression caffeine cardiovascular disease gene regulation genetics genomics genotype-environment interaction human massively parallel reporter assay

主题词内皮细胞(Endothelial Cells);咖啡因(Caffeine);基因表达调控(Gene Expression Regulation);数量性状基因座位(Quantitative Trait Loci)

DOI 10.7554/eLife.85235

PMID 38334359

发布时间 2024-05-30

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准确一般字义偏差语意偏离译文作用小提交