Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.

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作者： Jie,Li ^[1] ; Francesca,Moretti ^[2] ; Tunda,Hidvegi ^[1] ; Sanja,Sviben ^[3] ; James A J,Fitzpatrick ^[4] ; Hemalatha,Sundaramoorthi ^[1] ; Stephen C,Pak ^[1] ; Gary A,Silverman ^[1] ; Britta,Knapp ^[2] ; Ireos,Filipuzzi ^[2] ; John,Alford ^[5] ; John,Reece-Hoyes ^[5] ; Florian,Nigsch ^[2] ; Leon O,Murphy ^[5] ; Beat,Nyfeler ^[2] ; David H,Perlmutter ^[6]

作者单位： Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri. ^[1] Novartis Biomedical Research, Basel, Switzerland. ^[2] Center for Cellular Imaging, Washington University School of Medicine, St. Louis, Missouri. ^[3] Center for Cellular Imaging, Washington University School of Medicine, St. Louis, Missouri; Department of Cell Biology, Washington University School of Medicine, St. Louis, Missouri; Department of Neuroscience, Washington University School of Medicine, St. Louis, Missouri. ^[4] Novartis Biomedical Research, Cambridge, Massachusetts. ^[5] Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri. Electronic address: perlmutterd@wustl.edu. ^[6]

关键词 Aggregation-Prone Proteins Autophagy Liver Disease Proteasome α1-Antitrypsin Deficiency

主题词 α1抗胰蛋白酶缺乏症(alpha 1-Antitrypsin Deficiency);人类(Humans);溶酶体(Lysosomes);α1抗胰蛋白酶(alpha 1-Antitrypsin);内质网(Endoplasmic Reticulum);自噬(Autophagy)

DOI 10.1016/j.jcmgh.2024.02.006

PMID 38336172

发布时间 2024-09-20

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Cellular and molecular gastroenterology and hepatology

2024年17卷6期

1007-1024页

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Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.

Cellular and molecular gastroenterology and hepatology

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Cellular and molecular gastroenterology and hepatology

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Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin Deficiency.

Cellular and molecular gastroenterology and hepatology

相似文献

Cellular and molecular gastroenterology and hepatology

相关期刊

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