Fluorescence detecting glycopeptide antibiotics via a dynamic molecular switch.

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作者： Xiaomei,Zou ^[1] ; Yanting,Lin ^[2] ; Shihui,Zhang ^[3] ; Tao,Deng ^[4] ; Ximing,Xu ^[5] ; Yingchun,Zhou ^[6] ; Zhihui,Liu ^[1] ; Weiguo,Lu ^[1] ; Qingzhong,Hu ^[2] ; Chaozhan,Lin ^[2] ; Chenchen,Zhu ^[7] ; Fang,Liu ^[8]

作者单位： The First Clinical Medical College and the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. ^[1] School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. ^[2] Artemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. ^[3] School of Medicine, Foshan University, Foshan, 528000, PR China. ^[4] School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266071, PR China. ^[5] The First Clinical Medical College and the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. Electronic address: yingchunbaby@126.com. ^[6] School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. Electronic address: zhucc@gzucm.edu.cn. ^[7] School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China. Electronic address: fangliu@gzucm.edu.cn. ^[8]

关键词 2′,7′-dichlorofluorescein Dynamic molecular switch Fluorescence probes Glycopeptide antibiotics (GPAs)Vancomycin

主题词荧光(Fluorescence);抗菌药(Anti-Bacterial Agents);糖肽类(Glycopeptides);万古霉素(Vancomycin);丙氨酸(Alanine)

DOI 10.1016/j.aca.2024.342309

PMID 38336411

发布时间 2024-02-14

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