Novel 1-(1-Arylimiazolin-2-Yl)-3-Arylalkilurea Derivatives with Modulatory Activity on Opioid MOP Receptors.

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作者： Dominik,Straszak ^[1] ; Sylwia,Woźniak ^[1] ; Agata,Siwek ^[2] ; Monika,Głuch-Lutwin ^[2] ; Marcin,Kołaczkowski ^[2] ; Aldona,Pietrzak ^[3] ; Bartłomiej,Drop ^[4] ; Dariusz,Matosiuk ^[1]

作者单位： Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University, Chodzki 4A, 20-093 Lublin, Poland. ^[1] Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland. ^[2] Department of Dermatology, Venereology, and Paediatric Dermatology, Faculty of Medicine, Medical University, Staszica 11, 20-080 Lublin, Poland. ^[3] Department of Medical Informatics and Statistics, Medical University, Jaczewskiego 4, 20-090 Lublin, Poland. ^[4]

关键词 1-aryl-2-aminoimidazoline-2 MOP receptor OP3 receptor allosterism β-arrestin

主题词人类(Humans);受体, 阿片样(Receptors, Opioid);受体, 阿片样, μ(Receptors, Opioid, mu);镇痛药, 阿片类(Analgesics, Opioid);镇痛药(Analgesics)

DOI 10.3390/molecules29030571

PMID 38338317

发布时间 2024-02-14

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