Influence of Physiological Variables and Comorbidities on Plasma Aβ40, Aβ42, and p-tau181 Levels in Cognitively Unimpaired Individuals.

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第一作者： Francisco,Martínez-Dubarbie

第一单位： Neurology Service, Marqués de Valdecilla University Hospital, 39008 Santander, Spain.

作者： Francisco,Martínez-Dubarbie ^[1] ; Armando,Guerra-Ruiz ^[2] ; Sara,López-García ^[3] ; Juan,Irure-Ventura ^[1] ; Carmen,Lage ^[2] ; Marta,Fernández-Matarrubia ^[2] ; Ana,Pozueta-Cantudo ^[4] ; María,García-Martínez ^[1] ; Andrea,Corrales-Pardo ^[2] ; María,Bravo ^[5] ; Juan,Martín-Arroyo ^[1] ; Jon,Infante ^[2] ; Marcos,López-Hoyos ^[1] ; María Teresa,García-Unzueta ^[2] ; Pascual,Sánchez-Juan ^[1] ; Eloy,Rodríguez-Rodríguez ^[2]

作者单位： Neurology Service, Marqués de Valdecilla University Hospital, 39008 Santander, Spain. ^[1] Institute for Research Marqués de Valdecilla (IDIVAL), 39011 Santander, Spain. ^[2] Biochemistry and Clinical Analysis Department, Marqués de Valdecilla University Hospital, 39008 Santander, Spain. ^[3] Immunology Department, Marqués de Valdecilla University Hospital, 39008 Santander, Spain. ^[4] Atlantic Fellow for Equity in Brain Health, Global Brain Health Institute, University of California, San Francisco, CA 94143, USA. ^[5] Health Sciences Department, Universidad Europea del Atlántico, 39011 Santander, Spain. ^[6] Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), 28220 Madrid, Spain. ^[7] Medicine and Psychiatry Department, University of Cantabria, 39011 Santander, Spain. ^[8] Molecular Biology Department, University of Cantabria, 39011 Santander, Spain. ^[9] CIEN Foundation, Queen Sofia Foundation Alzheimer Center, 28220 Madrid, Spain. ^[10]

关键词 Alzheimer’s disease amyloid comorbidities plasma biomarkers presymptomatic stages tau protein

主题词人类(Humans);淀粉样β肽类(Amyloid beta-Peptides);阿尔茨海默病(Alzheimer Disease);共病现象(Comorbidity);tau蛋白质类(tau Proteins);肽碎片(Peptide Fragments)

DOI 10.3390/ijms25031481

PMID 38338759

发布时间 2024-02-14

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