Directed Evolution of 4-Hydroxyphenylpyruvate Biosensors Based on a Dual Selection System.

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第一作者： Hongxuan,Du

第一单位： School of Life Science, Northeast Forestry University, Harbin 150040, China.

作者： Hongxuan,Du ^[1] ; Yaoyao,Liang ^[2] ; Jianing,Li ^[3] ; Xinyao,Yuan ^[1] ; Fenglin,Tao ^[2] ; Chengjie,Dong ^[3] ; Zekai,Shen ^[1] ; Guangchao,Sui ^[2] ; Pengchao,Wang ^[1]

作者单位： School of Life Science, Northeast Forestry University, Harbin 150040, China. ^[1] NEFU-China iGEM Team, Northeast Forestry University, Harbin 150040, China. ^[2] Key Laboratory for Enzyme and Enzyme-Like Material Engineering of Heilongjiang, College of Life Science, Northeast Forestry University, Harbin 150040, China. ^[3] Aulin College, Northeast Forestry University, Harbin 150040, China. ^[4] School of Pharmacology, China Pharmaceutical University, Nanjing 210009, China. ^[5]

关键词 PobR aromatic compound directed evolution dual selection system ligand specificity

主题词反式激活因子类(Trans-Activators);大肠杆菌(Escherichia coli);转录因子(Transcription Factors);生物传感技术(Biosensing Techniques);苯丙酮酸类(Phenylpyruvic Acids)

DOI 10.3390/ijms25031533

PMID 38338812

发布时间 2024-02-14

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