Assessment of the mechanistic role of an Indian traditionally used ayurvedic herb Bacopa monnieri (L.)Wettst. for ameliorating oxidative stress in neuronal cells.

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第一作者： Souvik,Ghosh

第一单位： Molecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India; Biomaterials and Multiscale Mechanics Laboratory, Department of Metallurgical and Materials Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India; Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.

作者： Souvik,Ghosh ^[1] ; Viney,Kumar ^[2] ; Haimanti,Mukherjee ^[2] ; Saakshi,Saini ^[2] ; Sumeet,Gupta ^[3] ; Samrat,Chauhan ^[4] ; Komal,Kushwaha ^[5] ; Debrupa,Lahiri ^[6] ; Debabrata,Sircar ^[5] ; Partha,Roy ^[7]

作者单位： Molecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India; Biomaterials and Multiscale Mechanics Laboratory, Department of Metallurgical and Materials Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India; Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. ^[1] Molecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. ^[2] Department of Pharmacy, Maharshi Markandeshwar University (Deemed to Be University), Mullana, Haryana, 133207, India. ^[3] Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, 140401, India. ^[4] Plant Molecular Biology Group, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. ^[5] Biomaterials and Multiscale Mechanics Laboratory, Department of Metallurgical and Materials Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India; Centre of Nanotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. ^[6] Molecular Endocrinology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. Electronic address: partha.roy@bt.iitr.ac.in. ^[7]

关键词 Bacopasaponin C Bacopaside II Bacopaside X Bacoside A3 Neuroprotection Nrf-2/Keap1 Oxidative stress