Circ-FOXO3 inhibits triple-negative breast cancer growth and metastasis via regulating WHSC1-H3K36me2-Zeb2 axis.

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第一作者： Danyang,Chen

第一单位： Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou Key Laboratory of "Translational Medicine on Malignant Tumor Treatment", Guangzhou, Guangdong, China.

作者： Danyang,Chen ^[1] ; Shanshan,Zeng ^[1] ; Huisi,Qiu ^[2] ; Mingqiang,Yang ^[1] ; Xin,Lin ^[1] ; Xinwu,Lv ^[3] ; Pan,Li ^[1] ; Shaojuan,Weng ^[1] ; Siyue,Kou ^[1] ; Kai,Luo ^[1] ; Zongcai,Liu ^[4] ; Yanmei,Yi ^[5] ; Hao,Liu ^[6]

作者单位： Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou Key Laboratory of "Translational Medicine on Malignant Tumor Treatment", Guangzhou, Guangdong, China. ^[1] The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, Guangdong, China. ^[2] School of Basic Medical Sciences, Guangdong Medical University, Zhanjiang, Guangdong, China. ^[3] Laboratory of Endocrinology and Metabolism, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic address: liuzongcai800@sina.com. ^[4] School of Basic Medical Sciences, Guangdong Medical University, Zhanjiang, Guangdong, China. Electronic address: yiymei@gdmu.edu.cn. ^[5] Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou Key Laboratory of "Translational Medicine on Malignant Tumor Treatment", Guangzhou, Guangdong, China. Electronic address: liuhao@gzhmu.edu.cn. ^[6]

关键词 H3K36me2 modification Triple-negative breast cancer Tumor suppressor WHSC1 circ-FOXO3

主题词人类(Humans);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);微RNAs(MicroRNAs)

DOI 10.1016/j.cellsig.2024.111079

PMID 38341124

发布时间 2024-03-22

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