首页> Journal of molecular biology> Synonymous Mutations Can Alter Protein Dimerization Through Localized Interface Misfolding Involving Self-entanglements.

Synonymous Mutations Can Alter Protein Dimerization Through Localized Interface Misfolding Involving Self-entanglements.

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第一作者： Pham Dang,Lan

第一单位： Institute for Computational Sciences and Technology, Ho Chi Minh City, Viet Nam; Faculty of Physics and Engineering Physics, VNUHCM-University of Science, 227, Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam.

作者： Pham Dang,Lan ^[1] ; Daniel Allen,Nissley ^[2] ; Ian,Sitarik ^[2] ; Quyen V,Vu ^[3] ; Yang,Jiang ^[2] ; Philip,To ^[4] ; Yingzi,Xia ^[4] ; Stephen D,Fried ^[5] ; Mai Suan,Li ^[6] ; Edward P,O'Brien ^[7]

作者单位： Institute for Computational Sciences and Technology, Ho Chi Minh City, Viet Nam; Faculty of Physics and Engineering Physics, VNUHCM-University of Science, 227, Nguyen Van Cu Street, District 5, Ho Chi Minh City, Viet Nam. ^[1] Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA. ^[2] Institute of Physics, Polish Academy of Sciences, 02-668 Warsaw, Poland. ^[3] Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA. ^[4] Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA; Thomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218, USA. ^[5] Institute for Computational Sciences and Technology, Ho Chi Minh City, Viet Nam; Institute of Physics, Polish Academy of Sciences, 02-668 Warsaw, Poland. ^[6] Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA; Bioinformatics and Genomics Graduate Program, The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA; Institute for Computational and Data Sciences, Pennsylvania State University, University Park, PA 16802, USA. Electronic address: epo2@psu.edu. ^[7]

关键词 co-translational folding function kinetics mRNA misfolding non-equilibrium protein folding

医学主题词大肠杆菌(Escherichia coli);外切核糖核酸酶类(Exoribonucleases);动力学(Kinetics);蛋白质折叠(Protein Folding);蛋白质多聚化(Protein Multimerization);细胞膜(Cell Membrane)

DOI 10.1016/j.jmb.2024.168487

PMID 38341172

发布时间 2024-07-23

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