The HN protein of Newcastle disease virus induces cell apoptosis through the induction of lysosomal membrane permeabilization.

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作者： Yu,Chen ^[1] ; Shanshan,Zhu ^[2] ; Tianxing,Liao ^[3] ; Chunxuan,Wang ^[1] ; Jiajun,Han ^[1] ; Zhenyu,Yang ^[1] ; Xiaolong,Lu ^[1] ; Zenglei,Hu ^[1] ; Jiao,Hu ^[1] ; Xiaoquan,Wang ^[2] ; Min,Gu ^[3] ; Ruyi,Gao ^[2] ; Kaituo,Liu ^[4] ; Xiaowen,Liu ^[1] ; Chan,Ding ^[2] ; Shunlin,Hu ^[3] ; Xiufan,Liu ^[1]

作者单位： Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University; Yangzhou, Jiangsu, China. ^[1] Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, China. ^[2] Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, China. ^[3] Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou University, Yangzhou, China. ^[4] Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China. ^[5]

主题词动物(Animals);新城疫病毒(Newcastle disease virus);HN蛋白质(HN Protein);组织蛋白酶B(Cathepsin B);细胞凋亡(Apoptosis);溶酶体(Lysosomes)

DOI 10.1371/journal.ppat.1011981

PMID 38354122

发布时间 2024-02-17

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