Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease.

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第一作者： Suzanne K,Shoffner-Beck

第一单位： Department of Biomedical Engineering.

作者： Suzanne K,Shoffner-Beck ^[1] ; Lisa,Abernathy-Close ^[2] ; Stephanie,Lazar ^[2] ; Feiyang,Ma ^[3] ; Mehrnaz,Gharaee-Kermani ^[3] ; Amy,Hurst ^[2] ; Craig,Dobry ^[4] ; Deepika,Pandian ^[2] ; Rachael,Wasikowski ^[4] ; Amanda,Victory ^[2] ; Kelly,Arnold ^[1] ; Johann E,Gudjonsson ^[4] ; Lam C,Tsoi ^[5] ; J Michelle,Kahlenberg ^[3]

作者单位： Department of Biomedical Engineering. ^[1] Department of Internal Medicine, Division of Rheumatology. ^[2] Department of Internal Medicine, Division of Rheumatology.;Department of Dermatology, and. ^[3] Department of Dermatology, and. ^[4] Department of Dermatology, and.;Department of Computational Medicine and Bioinformatics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA. ^[5]

关键词 Autoimmune diseases Autoimmunity Collagens Dermatology Skin

主题词人类(Humans);瘢痕(Cicatrix);红斑狼疮, 皮肤(Lupus Erythematosus, Cutaneous);细胞因子类(Cytokines);红斑狼疮, 系统性(Lupus Erythematosus, Systemic);表型(Phenotype);转化生长因子β(Transforming Growth Factor beta);成纤维细胞(Fibroblasts)

DOI 10.1172/jci.insight.173437

PMID 38358820

发布时间 2025-01-08

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2024年9卷6期

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Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease.

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Lupus dermal fibroblasts are proinflammatory and exhibit a profibrotic phenotype in scarring skin disease.

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