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Preparation, Optimization and <i>In Vitro</i> Characterization of Fluticasoneloaded Mixed Micelles Based on Stearic Acid-g-chitosan as a Pulmonary Delivery System.

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第一作者： Shima,Tasharoie

第一单位： Drug and Food Control Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.;Aerosol Research Laboratory, Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

作者： Shima,Tasharoie ^[1] ; Seyed Naser,Ostad ^[2] ; Mohsen,Amini ^[3] ; Reyhaneh,Sabourian ^[4] ; Kambiz,Gilani ^[5]

作者单位： Drug and Food Control Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.;Aerosol Research Laboratory, Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. ^[1] Department of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. ^[2] Department of Medicinal Chemistry, School of Pharmacy, Tehran University of Medical Science, Tehran, Iran. ^[3] Drug and Food Control Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. ^[4] Aerosol Research Laboratory, Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.;Medicinal Plants Research Center, Tehran University of Medical Sciences, Tehran, Iran. ^[5]

关键词 Fluticasone propionate Vitamin E TPGS dipalmitoylphosphatidylcholine.optimization design polymeric micelle pulmonary delivery