CircPCNXL2 promotes tumor growth and metastasis by interacting with STRAP to regulate ERK signaling in intrahepatic cholangiocarcinoma.

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作者： Shuochen,Liu ^[1] ; Yirui,Wang ^[1] ; Tianlin,Wang ^[1] ; Kuangheng,Shi ^[1] ; Shilong,Fan ^[1] ; Chang,Li ^[1] ; Ruixiang,Chen ^[1] ; Jifei,Wang ^[1] ; Wangjie,Jiang ^[1] ; Yaodong,Zhang ^[1] ; Yananlan,Chen ^[1] ; Xiao,Xu ^[1] ; Yue,Yu ^[1] ; Changxian,Li ^[2] ; Xiangcheng,Li ^[3]

作者单位： Hepatobiliary Center, Key Laboratory of Liver Transplantation, The First Affiliated Hospital of Nanjing Medical University, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, Jiangsu Province, China. ^[1] Hepatobiliary Center, Key Laboratory of Liver Transplantation, The First Affiliated Hospital of Nanjing Medical University, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, Jiangsu Province, China. doclicx20@163.com. ^[2] Hepatobiliary Center, Key Laboratory of Liver Transplantation, The First Affiliated Hospital of Nanjing Medical University, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, Jiangsu Province, China. drxcli@njmu.edu.cn. ^[3] Wuxi People's Hospital, Wuxi Medical Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Nanjing Medical University, Wuxi, Jiangsu Province, China. drxcli@njmu.edu.cn. ^[4]

关键词 CircPCNXL2 Intrahepatic cholangiocarcinoma MEK/ERK signaling STRAP Trametinib