Novel Screening System for Biliary Excretion of Drugs Using Human Cholangiocyte Organoid Monolayers with Directional Drug Transport.

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第一作者： Kenta,Mizoi

第一单位： Faculty of Pharmacy, Takasaki University of Health and Welfare.

作者： Kenta,Mizoi ^[1] ; Ryo,Okada ^[2] ; Arisa,Mashimo ^[3] ; Norio,Masuda ^[1] ; Manabu,Itoh ^[4] ; Seiichi,Ishida ^[5] ; Daiju,Yamazaki ^[3] ; Takuo,Ogihara ^[6]

作者单位： Faculty of Pharmacy, Takasaki University of Health and Welfare. ^[1] School of Pharmacy, International University of Health and Welfare. ^[2] JSR-Keio University Medical and Chemical Innovation Center (JKiC), JSR Corporation. ^[3] Kendai Translational Research Center (KTRC). ^[4] MEDICAL & BIOLOGICAL LABORATORIES CO., LTD. (MBL). ^[5] Division of Applied Life Science, Graduate School of Engineering, Sojo University. ^[6] Division of Pharmacology, Center for Biological Safety and Research, National Institute of Health Sciences. ^[7] Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare. ^[8]

关键词 P-glycoprotein biliary excretion breast cancer resistance protein cholangiocyte organoid directional drug transport multidrug resistance-associated protein 2